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1

Rosemary Essential Oil-Loaded Lipid Nanoparticles: In Vivo Topical Activity from Gel Vehicles

Montenegro, Lucia, Pasquinucci, Lorella, Zappalà, Agata, Chiechio, Santina, Turnaturi, Rita, Parenti, Carmela

Journal:

Year:

2017

Language:

english

File:

PDF, 2.19 MB

english, 2017

2

Development, characterization, and in vitro and in vivo evaluation of benzocaine- and lidocaine-loaded nanostructrured lipid carriers

Carmelo Puglia, Maria Grazia Sarpietro, Francesco Bonina, Francesco Castelli, Magda Zammataro, Santina Chiechio

Journal:

Journal of Pharmaceutical Sciences

Year:

2011

Language:

english

File:

PDF, 276 KB

english, 2011

3

Acetyl- L -carnitine: from a biological curiosity to a drug for the peripheral nervous system and beyond

Onofrj, Marco, Ciccocioppo, Fausta, Varanese, Sara, di Muzio, Antonio, Calvani, Menotti, Chiechio, Santina, Osio, Maurizio, Thomas, Astrid

Journal:

Expert Review of Neurotherapeutics

Year:

2013

Language:

english

File:

PDF, 1.03 MB

english, 2013

4

Mice Lacking Central Serotonergic Neurons Show Enhanced Inflammatory Pain and an Impaired Analgesic Response to Antidepressant Drugs

Zhao, Z.-Q., Chiechio, S., Sun, Y.-G., Zhang, K.-H., Zhao, C.-S., Scott, M., Johnson, R. L., Deneris, E. S., Renner, K. J., Gereau, R. W., Chen, Z.-F.

Journal:

Journal of Neuroscience

Year:

2007

Language:

english

File:

PDF, 498 KB

english, 2007

5

L-Acetylcarnitine: A Proposed Therapeutic Agent for Painful Peripheral Neuropathies

Chiechio, S., Copani, A., Nicoletti, F., Gereau IV, R.

Journal:

Current Neuropharmacology

Year:

2006

Language:

english

File:

PDF, 105 KB

english, 2006

6

An evaluation of efficacy and safety of reboxetine in elderly patients affected by “retarded” post-stroke depression: A random, placebo-controlled study

Liborio Rampello, Alessandro Alvano, Santina Chiechio, Rocco Raffaele, Ignazio Vecchio, Mariano Malaguarnera

Journal:

Archives of Gerontology and Geriatrics

Year:

2005

Language:

english

File:

PDF, 122 KB

english, 2005

7

mGlu2 metabotropic glutamate receptors restrain inflammatory pain and mediate the analgesic activity of dual mGlu2/mGlu3 receptor agonists

Zammataro, Magda, Chiechio, Santina, Montana, Michael C, Traficante, Anna, Copani, Agata, Nicoletti, Ferdinando, Gereau, Robert W

Journal:

Year:

2011

Language:

english

File:

PDF, 283 KB

english, 2011

8

Histaminergic mechanisms in clonidine induced analgesia in rat tail-flick test

R. Arrigo-Reina, S. Chiechio

Journal:

Inflammation Research

Year:

1995

Language:

english

File:

PDF, 242 KB

english, 1995

9

Increased analgesic potency of morphine following repeated anaphylactoid reaction by compound 48/80 involves cyclooxygenase products of arachidonic acid

R. Arrigo-Reina, S. Chiechio, Tiziana Catti

Journal:

Inflammation Research

Year:

1993

Language:

english

File:

PDF, 214 KB

english, 1993

10

Evidence of a key-role for histamine from mast cells in the analgesic effect of clomipramine in rats

R. Arrigo-Reina, S. Chiechio

Journal:

Inflammation Research

Year:

1998

Language:

english

File:

PDF, 141 KB

english, 1998

11

Prediction of the response to citalopram and reboxetine in post-stroke depressed patients

Liborio Rampello, Santina Chiechio, Giovanni Nicoletti, Alessandro Alvano, Ignazio Vecchio, Rocco Raffaele, Mariano Malaguarnera

Journal:

Psychopharmacology

Year:

2004

Language:

english

File:

PDF, 191 KB

english, 2004

12

β-Amyloid-activated cell cycle in SH-SY5Y neuroblastoma cells

Giuseppina Frasca, Santina Chiechio, Carlo Vancheri, Ferdinando Nicoletti, Agata Copani, Maria Angela Sortino

Journal:

Journal of Molecular Neuroscience

Year:

2004

Language:

english

File:

PDF, 107 KB

english, 2004

13

Hyperalgesic activity of kisspeptin in mice

Spampinato, Simona, Trabucco, Angela, Biasiotta, Antonella, Biagioni, Francesca, Cruccu, Giorgio, Copani, Agata, Colledge, William H, Sortino, Maria, Nicoletti, Ferdinando, Chiechio, Santina

Journal:

Year:

2011

Language:

english

File:

PDF, 1.05 MB

english, 2011

14

Metabotropic glutamate receptors and the control of chronic pain

Santina Chiechio, Ferdinando Nicoletti

Journal:

Current Opinion in Pharmacology

Year:

2012

Language:

english

File:

PDF, 319 KB

english, 2012

15

Curcumin loaded NLC induces histone hypoacetylation in the CNS after intraperitoneal administration in mice

Carmelo Puglia, Giuseppina Frasca, Teresa Musumeci, Luisa Rizza, Giovanni Puglisi, Francesco Bonina, Santina Chiechio

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2012

Language:

english

File:

PDF, 445 KB

english, 2012

16

Effects of phenformin on the proliferation of human tumor cell lines

Filippo Caraci, Mariangela Chisari, Giuseppina Frasca, Santina Chiechio, Salvatore Salomone, Antonio Pinto, Maria Angela Sortino, Alfredo Bianchi

Journal:

Year:

2003

Language:

english

File:

PDF, 205 KB

english, 2003

17

Novel neuronal targets for the acetylcholinesterase inhibitor donepezil

M.A. Sortino, G. Frasca, M. Chisari, P. Platania, S. Chiechio, C. Vancheri, A. Copani, P.L. Canonico

Journal:

Neuropharmacology

Year:

2004

Language:

english

File:

PDF, 225 KB

english, 2004

18

Transcriptional regulation of type-2 metabotropic glutamate receptors: an epigenetic path to novel treatments for chronic pain

Santina Chiechio, Agata Copani, Magda Zammataro, Giuseppe Battaglia, Robert W. Gereau IV, Ferdinando Nicoletti

Journal:

Trends in Pharmacological Sciences

Year:

2010

Language:

english

File:

PDF, 535 KB

english, 2010

19

An increased expression of the mGlu5 receptor protein following LTP induction at the perforant path–dentate gyrus synapse in freely moving rats

D. Manahan-Vaughan, R.T. Ngomba, M. Storto, A. Kulla, M.V. Catania, S. Chiechio, L. Rampello, F. Passarelli, A. Capece, K.G. Reymann, F. Nicoletti

Journal:

Neuropharmacology

Year:

2003

Language:

english

File:

PDF, 294 KB

english, 2003

20

Beta-Amyloid Monomer and Insulin/IGF-1 Signaling in Alzheimer's Disease

Giuffrida, Maria Laura, Tomasello, Flora, Caraci, Filippo, Chiechio, Santina, Nicoletti, Ferdinando, Copani, Agata

Journal:

Molecular Neurobiology

Year:

2012

Language:

english

File:

PDF, 238 KB

english, 2012

21

Evidence of correlations between morphine analgesia and H3-histamine receptors

R. Arrigo-Reina, S. Chiechio, C. Spadaro

Journal:

Pharmacological Research

Year:

1995

Language:

english

File:

PDF, 135 KB

english, 1995

22

Pregabalin in the Treatment of Chronic Pain

S. Chiechio, M. Zammataro, F. Caraci, L. Rampello, A. Copani, A. F. Sabato, Dr Ferdinando Nicoletti

Journal:

Clinical Drug Investigation

Year:

2009

Language:

english

File:

PDF, 150 KB

english, 2009

23

Transcriptional regulation of metabotropic glutamate receptor 2/3 expression by the NF-κB pathway in primary dorsal root ganglia neurons: a possible mechanism for the analgesic effect of L-acetylcarnitine

Santina Chiechio, Agata Copani, Laura De Petris, Maria Elena P Morales…

Journal:

Year:

2006

Language:

english

File:

PDF, 1.03 MB

english, 2006

24

H3-histamine receptors and clonidine analgesia in rats

S. Chiechio, C. Spadaro, R. Arrigo-Reina

Journal:

Inflammation Research

Year:

1997

Language:

english

File:

PDF, 93 KB

english, 1997

25

The role of brain cathecholamines on cholecystokinin induced analgesia in rat

SPADARO, C, CHIECHIO, S, ARRIGOREINA, R

Journal:

Pharmacological Research

Year:

1995

Language:

english

File:

PDF, 138 KB

english, 1995

26

Inhibition of pain response in the formalin test by naloxone in normal- or cold-.restrained-rats

Journal:

Pharmacological Research

Year:

1992

Language:

english

File:

PDF, 89 KB

english, 1992

27

Acetyl-L-Carnitine in Neuropathic Pain

Chiechio, Santina, Copani, Agata, Gereau, Robert W, Nicoletti, Ferdinando

Journal:

Year:

2007

Language:

english

File:

PDF, 123 KB

english, 2007

28

Lmx1b Is Required for Maintenance of Central Serotonergic Neurons and Mice Lacking Central Serotonergic System Exhibit Normal Locomotor Activity

Zhao, Z.-Q., Scott, M., Chiechio, S., Wang, J.-S., Renner, K. J., Gereau, R. W., Johnson, R. L., Deneris, E. S., Chen, Z.-F.

Journal:

Journal of Neuroscience

Year:

2006

Language:

english

File:

PDF, 560 KB

english, 2006

29

Epigenetic Modulation of mGlu2 Receptors by Histone Deacetylase Inhibitors in the Treatment of Inflammatory Pain

Chiechio, S., Zammataro, M., Morales, M. E., Busceti, C. L., Drago, F., Gereau, R. W., Copani, A., Nicoletti, F.

Journal:

Molecular Pharmacology

Year:

2009

Language:

english

File:

PDF, 385 KB

english, 2009

30

HDAC and HAT inhibitors differently affect analgesia mediated by group II metabotropic glutamate receptors

Zammataro, Magda, Sortino, Maria, Parenti, Carmela, Gereau, Robert W, Chiechio, Santina

Journal:

Year:

2014

Language:

english

File:

PDF, 668 KB

english, 2014

31

L-Acetylcarnitine Induces Analgesia by Selectively Up-Regulating mGlu2 Metabotropic Glutamate Receptors

Journal:

Molecular Pharmacology

Year:

2002

Language:

english

File:

PDF, 323 KB

english, 2002

32

Evaluation of the Prophylactic Efficacy of Amitriptyline and Citalopram, Alone or in Combination, in Patients with Comorbidity of Depression, Migraine, and Tension-Type Headache

Rampello, Liborio, Alvano, Alessandro, Chiechio, Santina, Malaguarnera, Mariano, Raffaele, Rocco, Vecchio, Ignazio, Nicoletti, Francesco

Journal:

Neuropsychobiology

Year:

2004

Language:

english

File:

PDF, 81 KB

english, 2004

33

Bone morphogenetic protein-7 delays podocyte injury due to high glucose

De Petris, L., Hruska, K. A., Chiechio, S., Liapis, H.

Journal:

Nephrology Dialysis Transplantation

Year:

2007

Language:

english

File:

PDF, 745 KB

english, 2007

34

[Advances in Pharmacology] || Modulation of Chronic Pain by Metabotropic Glutamate Receptors

Chiechio, Santina

Year:

2016

Language:

english

File:

PDF, 1.08 MB

english, 2016

35

The SSRI, Citalopram, Improves Bradykinesia in Patients With Parkinson's Disease Treated with L-Dopa

Rampello, Liborio, Chiechio, Santina, Raffaele, Rocco, Vecchio, Ignazio, Nicoletti, Francesco

Journal:

Clinical Neuropharmacology

Year:

2002

Language:

english

File:

PDF, 1.46 MB

english, 2002

36

Repeated activation of delta opiod receptors counteracts nerve injury-induced TNF- up-regulation in the sciatic nerve of rats with neuropathic pain: A possible correlation with delta opiod receptors-mediated antiallodinic effect

Vicario, N., Parenti, R., Arico', G., Turnaturi, R., Scoto, G. M., Chiechio, S., Parenti, C.

Journal:

Year:

2016

Language:

english

File:

PDF, 300 KB

english, 2016

37

Monomeric ß-amyloid interacts with type-1 insulin-like growth factor receptors to provide energy supply to neurons

Giuffrida, Maria L., Tomasello, Marianna F., Pandini, Giuseppe, Caraci, Filippo, Battaglia, Giuseppe, Busceti, Carla, Di Pietro, Paola, Pappalardo, Giuseppe, Attanasio, Francesco, Chiechio, Santina, B

Journal:

Frontiers in Cellular Neuroscience

Year:

2015

Language:

english

File:

PDF, 4.06 MB

english, 2015

38

Chronic Treatment with Fluoxetine Induces Sex-Dependent Analgesic Effects and Modulates HDAC2 and mGlu2 Expression in Female Mice

Zammataro, Magda, Merlo, Sara, Barresi, Massimo, Parenti, Carmela, Hu, Huijuan, Sortino, Maria A., Chiechio, Santina

Journal:

Frontiers in Pharmacology

Year:

2017

Language:

english

File:

PDF, 1.34 MB

english, 2017

39

l-Acetylcarnitine: A Mechanistically Distinctive and Potentially Rapid-Acting Antidepressant Drug

Chiechio, Santina, Canonico, Pier, Grilli, Mariagrazia

Journal:

International Journal of Molecular Sciences

Year:

2017

Language:

english

File:

PDF, 634 KB

english, 2017

40

Involvement of the Heme-Oxygenase Pathway in the Antiallodynic and Antihyperalgesic Activity of Harpagophytum procumbens in Rats

Parenti, Carmela, Aricò, Giuseppina, Chiechio, Santina, Di Benedetto, Giulia, Parenti, Rosalba, Scoto, Giovanna

Journal:

Year:

2015

Language:

english

File:

PDF, 1.48 MB

english, 2015

41

(2S)-N-2-methoxy-2-phenylethyl-6,7-benzomorphan compound (2S-LP2): Discovery of a biased mu/delta opioid receptor agonist

Pasquinucci, Lorella, Turnaturi, Rita, Calò, Girolamo, Pappalardo, Francesco, Ferrari, Federica, Russo, Giulia, Arena, Emanuela, Montenegro, Lucia, Chiechio, Santina, Prezzavento, Orazio, Parenti, Car

Journal:

European Journal of Medicinal Chemistry

Year:

2019

File:

PDF, 2.15 MB

2019

42

(2S)-N-2-methoxy-2-phenylethyl-6,7-benzomorphan compound (2S-LP2): Discovery of a biased mu/delta opioid receptor agonist

Pasquinucci, Lorella, Turnaturi, Rita, Calò, Girolamo, Pappalardo, Francesco, Ferrari, Federica, Russo, Giulia, Arena, Emanuela, Montenegro, Lucia, Chiechio, Santina, Prezzavento, Orazio, Parenti, Car

Journal:

European Journal of Medicinal Chemistry

Year:

2019

Language:

english

File:

PDF, 2.15 MB

english, 2019

43

Simultaneous Activation of Mu and Delta Opioid Receptors Reduces Allodynia and Astrocytic Connexin 43 in an Animal Model of Neuropathic Pain

Vicario, Nunzio, Pasquinucci, Lorella, Spitale, Federica M., Chiechio, Santina, Turnaturi, Rita, Caraci, Filippo, Tibullo, Daniele, Avola, Roberto, Gulino, Rosario, Parenti, Rosalba, Parenti, Carmela

Journal:

Molecular Neurobiology

Year:

2019

Language:

english

File:

PDF, 3.37 MB

english, 2019

44

Preclinical evidence of enhanced analgesic activity of duloxetine complexed with succinyl-β-cyclodextrin: a comparative study with cyclodextrin complexes

Seggio, Mimimorena, Contino, Annalinda, Maccarrone, Giuseppe, Parenti, Carmela, Merlo, Sara, Pappalardo, Giuseppe, Giuffrida, Alessandro, Chiechio, Santina

Journal:

International Journal of Pharmaceutics

Year:

2019

Language:

english

File:

PDF, 915 KB

english, 2019

45

Progress in the development of more effective and safer analgesics for pain management

Turnaturi, Rita, Chiechio, Santina, Salerno, Loredana, Rescifina, Antonio, Pittalà, Valeria, Cantarella, Giuseppina, Tomarchio, Emilia, Parenti, Carmela, Pasquinucci, Lorella

Journal:

European Journal of Medicinal Chemistry

Year:

2019

Language:

english

File:

PDF, 4.72 MB

english, 2019

46

Exploiting the Power of Stereochemistry in Drug Action: 3-[(2 S ,6 S ,11 S )-8-Hydroxy-6,11-dimethyl-1,4,5,6-tetrahydro-2,6-methano-3-benzazocin-3(2 H )-yl]- N -phenylpropanamide as Potent Sigma-1 Receptor Antagonist

Turnaturi, Rita, Pasquinucci, Lorella, Chiechio, Santina, Grasso, Margherita, Marrazzo, Agostino, Amata, Emanuele, Dichiara, Maria, Prezzavento, Orazio, Parenti, Carmela

Journal:

ACS Chemical Neuroscience

Year:

2020

Language:

english

File:

PDF, 1.76 MB

english, 2020

47

Lipid Nanoparticle Inclusion Prevents Capsaicin-Induced TRPV1 Defunctionalization

Puglia, Carmelo, Santonocito, Debora, Bonaccorso, Angela, Musumeci, Teresa, Ruozi, Barbara, Pignatello, Rosario, Carbone, Claudia, Parenti, Carmela, Chiechio, Santina

Journal:

Year:

2020

File:

PDF, 1.51 MB

2020

48

Intercellular communication and ion channels in neuropathic pain chronicization

Vicario, Nunzio, Turnaturi, Rita, Spitale, Federica Maria, Torrisi, Filippo, ZappalÃ , Agata, Gulino, Rosario, Pasquinucci, Lorella, Chiechio, Santina, Parenti, Carmela, Parenti, Rosalba

Journal:

Inflammation Research

Year:

2020

File:

PDF, 1.83 MB

2020